Autoimmune diseases reflect a breakdown in self-tolerance that results from defects in thymic deletion of potentially autoreactive T cells (central tolerance) and in T-cell intrinsic and extrinsic mechanisms that normally control potentially autoreactive T cells in the periphery (peripheral tolerance). and also have a considerable financial impact. Thus, enhancing the knowledge of autoimmune illnesses and… Continue reading Autoimmune diseases reflect a breakdown in self-tolerance that results from defects
Tag: Rabbit Polyclonal to C-RAF (phospho-Thr269)
Recently, new complexities in cell fate decision for helper T cells
Recently, new complexities in cell fate decision for helper T cells have emerged. induces differentiation of na?ve CD4+ T cells to become regulatory T cells (Tregs). Th17 cells are now known to play an important role not only in the pathogenesis of inflammation and autoimmune diseases, but also host defense against extracellular bacteria. Conversely, extensive… Continue reading Recently, new complexities in cell fate decision for helper T cells