Autoimmune diseases reflect a breakdown in self-tolerance that results from defects in thymic deletion of potentially autoreactive T cells (central tolerance) and in T-cell intrinsic and extrinsic mechanisms that normally control potentially autoreactive T cells in the periphery (peripheral tolerance). and also have a considerable financial impact. Thus, enhancing the knowledge of autoimmune illnesses and… Continue reading Autoimmune diseases reflect a breakdown in self-tolerance that results from defects