The influenza neuraminidase (NA) inhibitors zanamivir oseltamivir and peramivir were all designed based on the knowledge that this transition state analogue of the cleaved sialic acid 2 2 3 N-acetyl neuraminic acid (DANA) was a weak inhibitor of NA. of substrate and IC50s were calculated after LCI-699 each 10 min interval up to 60 min.… Continue reading The influenza neuraminidase (NA) inhibitors zanamivir oseltamivir and peramivir were all