Objective Thioredoxin-2 (Trx2) a major antioxidant proteins in mitochondria enhances nitric oxide bioavailability and inhibits ASK1-reliant apoptosis in endothelial cells (EC). towards the non-transgenic littermates. Ischemia-initiated arteriogenesis in top of the limb was augmented in Trx2-TG mice. Trx2-TG mice also showed improved capillary formation and maturation in the low Rabbit Polyclonal to PDK1 (phospho-Tyr9). limb… Continue reading Objective Thioredoxin-2 (Trx2) a major antioxidant proteins in mitochondria enhances nitric