During serial passaging of rubella computer virus (RUB) in cell culture the dominant species of defective-interfering RNA (DI) generated includes an in-frame deletion between your capsid protein (C) gene and E1 glycoprotein gene leading to production of the C-E1 fusion protein that’s essential for maintenance of the DI (Tzeng & Frey 2006 A BHK cell… Continue reading During serial passaging of rubella computer virus (RUB) in cell culture