In the mammalian central nervous system (CNS) coupling of neurons by gap junctions (electrical synapses) increases during early postnatal development then decreases but increases in the mature CNS following neuronal injury such as ischemia traumatic brain injury and epilepsy. an ischemic model. In addition three other injury models in mouse mature cortical cultures were used:… Continue reading In the mammalian central nervous system (CNS) coupling of neurons by