Autotaxin (ENPP2/ATX) and lysophosphatidic acid (LPA) receptors represent two key players in regulating cancer progression. in LPA5 knockout (KO) mice compared to wild-type (WT) mice. LPA1- but not LPA2-KO mice also showed diminished melanoma-derived lung metastasis suggesting Glycitein that host LPA1 and LPA5 receptors play critical roles in the seeding of metastasis. The decrease in… Continue reading Autotaxin (ENPP2/ATX) and lysophosphatidic acid (LPA) receptors represent two key players
Tag: Glycitein
Background & seeks Chronic liver disease is characterized by fibrosis that
Background & seeks Chronic liver disease is characterized by fibrosis that may progress to cirrhosis. Results Nod2 deficiency protected mice from cholestatic but not toxin-induced liver injury and fibrosis. Most notably the hepatic bile acid concentration was lower in Nod2?/? mice than wild type mice following bile duct ligation for Rabbit polyclonal to APE1. 3… Continue reading Background & seeks Chronic liver disease is characterized by fibrosis that