Activation of the cellular tension pathways (c-Jun N-terminal kinase [JNK] and p38 mitogen-activated proteins [MAP] kinase) is associated with apoptosis. genes encoding Fas/FasL and tumor necrosis aspect receptor 1 (TNFR1)/TNF-α as well as the p53-governed Bax and Noxa genes. The pX-dependent expression of TNFR1/TNF-α and Fas/FasL mediates caspase 8 activation leading to Bet cleavage. In… Continue reading Activation of the cellular tension pathways (c-Jun N-terminal kinase [JNK] and