We previously described the isolation of due to its genetic interaction with Δand are specifically defective in ligand-induced degradation of Ste2p and α-factor Pravadoline and exhibit vacuole fragmentation directly upon a shift to 37°C. and Arl1p have closely related functions Δcells are defective in endocytic transport and in vacuolar protein sorting. Arfs constitute a ubiquitous… Continue reading We previously described the isolation of due to its genetic interaction