PLK (Polo-like kinase) inhibitors such as BI-2536 have already been reported to suppress (encoding IFNβ interferon β) gene transcription induced by AK-1 ligands that activate TLR3 (Toll-like receptor 3) and TLR4. family members displaces and associates them from acetylated lysine residues in histones. We discovered that Wager inhibitors that usually do not inhibit PLKs phenocopied… Continue reading PLK (Polo-like kinase) inhibitors such as BI-2536 have already been reported