Uracil-DNA glycosylase (UDG) compromises the replication strategies of diverse infections from unrelated lineages. subunits of p56 occupies the UDG DNA-binding cleft, whereas the dimer user interface forms a hydrophobic package to capture a mechanistically essential UDG residue. Remarkably, these p56 inhibitory components are unexpectedly analogous to features utilized by ugi despite serious architectural disparity. Connections… Continue reading Uracil-DNA glycosylase (UDG) compromises the replication strategies of diverse infections from