Optimal induction of p53 protein following DNA damage requires RPL26-mediated increases

Optimal induction of p53 protein following DNA damage requires RPL26-mediated increases in p53 mRNA translation. p53-mediated cell death after several different types of DNA damage and cellular stress. The ability to reduce stress induction of p53 with oligonucleotides or additional small molecules offers numerous potential restorative uses. mutations prospects to a serious susceptibility to malignancy… Continue reading Optimal induction of p53 protein following DNA damage requires RPL26-mediated increases