Leptin has been implicated in growth and tumorigenesis development, in obese patients particularly. way in both individual hepatocellular carcinoma HepG2 breasts and cell tumor MCF-7 cell. Reductions or Overexpression of APPL1 marketed or attenuated, respectively, leptin-induced 6902-77-8 IC50 phosphorylation of STAT3, ERK1/2, and Akt in the tumor cells, followed with improved or mitigated cellular migration… Continue reading Leptin has been implicated in growth and tumorigenesis development, in obese