The tetrameric single stranded (ss)DNA binding protein (((SSB (by protein to DNA binding denseness17; 18 as well as salt concentration and type with multivalent cations being more effective13; 14; 15; 16. (dT)35 molecule binds with high affinity whereas the second (dT)35 binds with much weaker affinity indicative of negative cooperativity that becomes more extreme because… Continue reading The tetrameric single stranded (ss)DNA binding protein (((SSB (by protein to