The Wnt signaling pathway is a robust regulator of skeletal homeostasis. Binding of Wnt ligands to a complicated of Frizzled and Lrp5 or Lrp6 co-receptors promotes the stabilization from the transcription element -catenin, formation of the complicated with TCF/LEF, and induction of Wnt focus on genes like and trigger high bone tissue mass [23], ,… Continue reading The Wnt signaling pathway is a robust regulator of skeletal homeostasis.