Expression of Pitx2 on the left side of the embryo patterns left-right (LR) organs including the dorsal mesentery (DM) whose asymmetric cell behavior directs gut looping. LR transcription of this locus essential for LR organogenesis. INTRODUCTION The external symmetry of vertebrates conceals left-right (LR) asymmetries of the internal organs essential for function and placement within… Continue reading Expression of Pitx2 on the left side of the embryo patterns