The Disks large (Dlg) scaffolding protein acts as a tumor suppressor regulating basolateral epithelial polarity and proliferation. reveal an unpredicted evolutionary diversity of the vertebrate Dlg family in basolateral epithelium formation. Abstract Graphical Abstract Shows ? Dlg3 contributes to apical epithelial polarity in the mouse embryo ? Dlg3 interactome study discovers TJ-associated proteins and polarity… Continue reading The Disks large (Dlg) scaffolding protein acts as a tumor suppressor