Supplementary MaterialsSupplementary data contains Figs. and IL-4 differentiation cocktail or IFN

Supplementary MaterialsSupplementary data contains Figs. and IL-4 differentiation cocktail or IFN and GM-CSF had been pulsed with tumor cell lysates and additional matured in the current presence of IFN and LPS (4-DCs and -DCs respectively). DCs were in that case found in co-culture assays with ova-specific T IFN and cells and IL-4 secretion measured by… Continue reading Supplementary MaterialsSupplementary data contains Figs. and IL-4 differentiation cocktail or IFN

Neutrophil elastase (NE) could be rapidly adopted by tumor cells that

Neutrophil elastase (NE) could be rapidly adopted by tumor cells that absence endogenous NE appearance, including breast cancer tumor, which leads to cross-presentation of PR1, an NE-derived HLA-A2-restricted peptide that’s an immunotherapy focus on in hematological and great tumor malignancies. double-digit nanomolar range (63.1 nm), indicative of a solid interaction with NRP1 (Fig. 3of 38.7… Continue reading Neutrophil elastase (NE) could be rapidly adopted by tumor cells that