The relevance of the adaptor protein TNF receptor-associated factor 2 (TRAF2) for signal transduction of the death receptor tumour necrosis factor receptor1 (TNFR1) is well-established. Grab3-self-employed apoptosis, we performed tests in HeLa cells that lack endogenous Grab3 and HeLa cells stably transfected with Grab3. HeLa cells, in which necroptosis offers no part, were markedly sensitised… Continue reading The relevance of the adaptor protein TNF receptor-associated factor 2 (TRAF2)