The third member of the Dickkopf family (DKK-3), also known as reduced expression in immortalized cells (REIC), is a tumor suppressor present in a variety of tumor cells. and c-Myc, the downstream transcription elements of the Wnt/-catenin signaling path, was inhibited pursuing treatment with DKK-3. A tumor cell viability assay verified the anti-proliferative results of… Continue reading The third member of the Dickkopf family (DKK-3), also known as