Background and Aims The gastric mucosa provides a stringent epithelial barrier and produces acid and enzymes that initiate digestion. coding mutations show virtual absence of mRNA and protein for the backbone of the major stomach mucin, MUC5AC. These observations correspond to a paucity of foveolar-cell secretory vesicles and notable loss of stomach but not intestinal… Continue reading Background and Aims The gastric mucosa provides a stringent epithelial barrier