Beta-amyloid (Aβ) in brain is a major factor involved in Alzheimer’s disease (AD) that results in severe memory deficit. site but not the Swe mutant site of APP for Aβ production explains the distinct inhibitor responses in the different AD mouse models. In contrast to cathepsin B the BACE1 β-secretase prefers to cleave the Swe… Continue reading Beta-amyloid (Aβ) in brain is a major factor involved in Alzheimer’s