Enteric inhibitory neurotransmission is an important feature of the neural regulation of gastrointestinal motility. ATP hyperpolarized EPZ011989 PDGFRα+ cells but depolarized SMCs. Only part of the ATP response in PDGFRα+ cells was blocked by MRS 2500 a P2Y1 antagonist. ADP MRS 2365 β-NAD and adenosine 5-diphosphate-ribose P2Y1 agonists hyperpolarized PDGFRα+ cells and these responses were… Continue reading Enteric inhibitory neurotransmission is an important feature of the neural regulation