Background Recurring deformation stimulates proliferation in individual Caco-2 intestinal epithelial cells via an ERK1/2-reliant pathway. -actinin-1, however, not -actinin-4 and paxillin, inhibited ERK1/2 and buy Procoxacin FAK phosphorylation, whereas Src activation is apparently independent of the effects. Conclusions The intestinal epithelial cell cytoskeleton might transduce mechanised indicators via -actinin-1 in to the focal adhesion complicated,… Continue reading Background Recurring deformation stimulates proliferation in individual Caco-2 intestinal epithelial cells