Leydig cells (LCs) are believed to differentiate from spindle-shaped precursor cells that exhibit some areas of differentiated function, including 3-hydroxysteroid dehydrogenase (3HSD) activity. the LC lineage (6, 12). In mice, the knockout of PDGF-A prevents LC advancement, revealing a possibly important function of PDGFR signaling in SLCs (12). The goals of today’s study had been… Continue reading Leydig cells (LCs) are believed to differentiate from spindle-shaped precursor cells