Toll-like receptors (TLRs) activate distinctive, yet overlapping pieces of signaling molecules,

Toll-like receptors (TLRs) activate distinctive, yet overlapping pieces of signaling molecules, resulting in inflammatory replies to pathogens. of macrophages contaminated with influenza stress A/PR/8/34 (PR8) and considerably improved success of PR8-contaminated mice. Hence, 2R9 represents a TLR-targeting agent that blocks proteins connections downstream of turned on TLRs. Graphical abstract Open up in another window Launch… Continue reading Toll-like receptors (TLRs) activate distinctive, yet overlapping pieces of signaling molecules,