Caveolin-1 (CAV1) offers been implicated in the regulation of several signaling

Caveolin-1 (CAV1) offers been implicated in the regulation of several signaling pathways and in oncogenesis. apoptosis, which were reversed by CAV1 re-expression. These results were recapitulated by PKC knockdown and re-expression in ESFT cells in which CAV1 was previously knocked down, therefore demonstrating that phospho(Thr638)-PKC functions downstream of CAV1 to determine the level of sensitivity… Continue reading Caveolin-1 (CAV1) offers been implicated in the regulation of several signaling