The CCCTC-binding factor CTCF is the just known vertebrate insulator protein and has been shown to regulate important developing processes such as imprinting, X-chromosome inactivation and genomic architecture. heterologous assays. In hESCs, CTCF is present in multisubunit proteins things and can become poly(ADP)ribosylated. Known CTCF cofactors, such as Cohesin, differentially co-localize in AZD6482 the area… Continue reading The CCCTC-binding factor CTCF is the just known vertebrate insulator protein