Endothelin-1 (ET-1), produced by the prostate epithelia, likely plays an important

Endothelin-1 (ET-1), produced by the prostate epithelia, likely plays an important role in the progression of prostate cancer. of the ETA may allow growth/survival. ET-1 treatment of prostate tumor cells significantly decreased paclitaxel-induced apoptosis through activation of the ETA subtype. The anti-apoptotic effects of ET-1 are mediated, at least Rabbit Polyclonal to DNAI2 in part,… Continue reading Endothelin-1 (ET-1), produced by the prostate epithelia, likely plays an important