A key query in immunology concerns how sterile injury activates innate immunity to mediate damaging inflammation in the lack of international invaders. of HMGB1 as a required and adequate mediator of swelling.] 3. Johns EW, Goodwin CHM, Walker JM, Sanders C. Chromosomal protein linked to histones. Ciba Found out. Symp. 1975;28:95C112. 4. Merenmies J, Pihlaskari… Continue reading A key query in immunology concerns how sterile injury activates innate