The polyamines, putrescine, spermine and spermidine, are ubiquitous multifunctional cations essential for cellular proliferation. researched using a range of inhibitors of polyamine biosynthesis, inducers of polyamine polyamine or catabolism mimetics. The many broadly utilized inhibitor is normally -difluoromethylornithine (DFMO) (Metcalf et al. 1978), an permanent inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme of polyamine… Continue reading The polyamines, putrescine, spermine and spermidine, are ubiquitous multifunctional cations essential