Dickkopf-related protein 3 (DKK3) is usually an antagonist of Wnt ligand activity. DKK3 suppressed cell colony formation through inducing G0/G1 cell cycle police arrest and apoptosis of breast tumour cells. DKK3 also caused changes of cell morphology, and inhibited breast tumour cell migration through curing epithelial-mesenchymal transition (EMT) and down-regulating come cell guns. DKK3 inhibited… Continue reading Dickkopf-related protein 3 (DKK3) is usually an antagonist of Wnt ligand