The phosphatidylinositol-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway is activated in even more than88% of glioblastomas (GBM). results had been mediated by lowers in the experience and appearance of choline kinase and lactate dehydrogenase, which respectively control Computer and lactate creation downstream of HIF-1. Treatment using the DNA harming agent temozolomide didn’t impact either biomarker… Continue reading The phosphatidylinositol-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway is activated in