Background The KMT2A/MLL1 lysine methyltransferase complex can be an epigenetic regulator of selected developmental genes, partly through the SET domain-catalysed methylation of H3K4. to Msk1 knockdown, as do degrees of H3K4 methylation and H3S10 phosphorylation at KTM2A focus on genes trithorax group protein TRX (trithorax), TRR (TRX-related) and dSET1 [1, 2]. Like their homologues, they… Continue reading Background The KMT2A/MLL1 lysine methyltransferase complex can be an epigenetic regulator