We examined the effect of the cellular sphingolipid level on the launch of arachidonic acid (AA) and activity of cytosolic phospholipase A2 (cPLA2) using two Chinese hamster ovary (CHO)-E1-derived mutants deficient in sphingolipid synthesis: LY-B cells defective in the LCB1 subunit of serine palmitoyltransferase for de novo synthesis of sphingolipid varieties, and LY-A cells defective… Continue reading We examined the effect of the cellular sphingolipid level on the