Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is one of the most

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is one of the most abundant RNA binding proteins. roles in gene expression by regulating the biogenesis and translation of messengers RNAs the processing of miRNAs affecting transcription and controlling telomere maintenance. The multiple functions of this protein correlate with diverse roles in genetic disease cancer and the replication… Continue reading Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is one of the most

History Genetic predisposition to life-threatening cardiac arrhythmias such as for example

History Genetic predisposition to life-threatening cardiac arrhythmias such as for example in congenital long-QT symptoms (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT) represent treatable factors behind sudden cardiac loss of life in adults and kids. whereas one subject matter with mutation p.Q136P died during exertion not surprisingly treatment suddenly. Mutations affect conserved residues located within… Continue reading History Genetic predisposition to life-threatening cardiac arrhythmias such as for example

Neonatal Fc receptors for immunoglobulin (Ig)G (FcRn) assume a central role

Neonatal Fc receptors for immunoglobulin (Ig)G (FcRn) assume a central role in regulating host IgG levels and IgG transport across polarized epithelial barriers. had been similar to those from contamination. Our data suggest that FcRn can be functionally expressed in the stomach which is involved in transcytosis of IgG and AT7519 HCl prevent colonization by… Continue reading Neonatal Fc receptors for immunoglobulin (Ig)G (FcRn) assume a central role