Some improved oligonucleotides (ONs), seen as a a phosphorothioate (P=S) backbone and a six-membered azasugar (6-AZS) being a sugar alternative within a nucleotide, were newly synthesized and assessed because of their capability to inhibit individual immunodeficiency virus type 1 (HIV-1) via basic treatment of HIV-1-contaminated cultures, without the transfection process. times. Taken jointly, our results… Continue reading Some improved oligonucleotides (ONs), seen as a a phosphorothioate (P=S) backbone