The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate

The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate hydrate continues to be realized through the use of easily available L-prolinamide as the catalyst. supplementary α-hydroxyphosphonates seem even more significant as all chiral organic amino acids are secondary amines. The optically enriched forms of secondary α-hydroxyphosphonates are mainly obtained through enzymatic methods 6… Continue reading The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate