Background Aberrant promoter DNA methylation has been shown to play a

Background Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia (AML) pathophysiology. observed in the patients. Conclusions/Significance Our study provides a comprehensive epigenetic profiling of AML, identifies new clinical markers for cases with a normal karyotype, and reveals relevant biological information related to the role of fusion proteins on… Continue reading Background Aberrant promoter DNA methylation has been shown to play a

The Myc/Utmost/Mad transcription factor network is involved with cell behavior; however,

The Myc/Utmost/Mad transcription factor network is involved with cell behavior; however, there is certainly small information on its genomic binding sites fairly. 1992; Davis et al. 1993) and latest research demonstrate that gene function is vital for hematopoiesis and organogenesis (de Alboran et al. 2001; Douglas et al. 2001; Trumpp et al. 2001; Knoepfler et… Continue reading The Myc/Utmost/Mad transcription factor network is involved with cell behavior; however,