Supplementary MaterialsSupplementary Physique 1. (and as mechanisms of resistance to third-generation TKIs targeting [11C13]. Finally, osimertinib resistance is being linked to either copy number gain, gene amplification, or mutations [14C16]. Methods Here, present the case of a patient with a metastatic lung adenocarcinoma. For the described study, we obtained tumor sample from lung tumor and… Continue reading Supplementary MaterialsSupplementary Physique 1. (and as mechanisms of resistance to third-generation
Tag: Rabbit polyclonal to ABHD14B
Germinal middle (GC) B cells cycle between two states, the light
Germinal middle (GC) B cells cycle between two states, the light zone (LZ) and the dark zone (DZ), and in the latter they proliferate and hypermutate their immunoglobulin genes. are consistent with a model where the switch from your LZ to the DZ is brought on after receipt of T cell help, and suggest that… Continue reading Germinal middle (GC) B cells cycle between two states, the light