This study was initiated to explore the result of recombinant rat

This study was initiated to explore the result of recombinant rat Crry linked to the Fc portion of rat IgG2a (Crry-Ig) within the induction of experimental autoimmune anterior uveitis (EAAU) and on established disease. rats. Importantly administration of Crry-Ig actually after the onset of EAAU resulted in a sharp decrease in the disease activity and… Continue reading This study was initiated to explore the result of recombinant rat

We investigated the role of microparticles in vascular dysfunction from the

We investigated the role of microparticles in vascular dysfunction from the multisystemic disorder of preeclampsia in women’s omental arteries or mouse arteries. induced up-regulation of inducible nitric-oxide synthase and COX-2 appearance evoked nuclear factor-κB activation and enhanced oxidative and nitrosative stress. Interestingly the microparticles originating most probably from leukocytes were responsible for the COX-2 vasoconstrictor… Continue reading We investigated the role of microparticles in vascular dysfunction from the

Proopiomelanocortin (POMC)-expressing neurons in the hypothalamus integrate a variety of central

Proopiomelanocortin (POMC)-expressing neurons in the hypothalamus integrate a variety of central and peripheral metabolic inputs and regulate energy homeostasis by controlling energy expenditure and food intake. target for the treatment of metabolic disorders such as obesity and diabetes attempts have been made to generate potent brain-penetrant PRCP inhibitors. Here we discuss the part of PRCP… Continue reading Proopiomelanocortin (POMC)-expressing neurons in the hypothalamus integrate a variety of central