Pharmacological agents suggested for infarct size limitation have severe unwanted effects when utilized at cardioprotective doses which hinders their translation into scientific practice. utilized as providers for heart-targeted medication delivery. for three minutes. Centrifuged solution was additional spectrophotometrically diluted and analyzed. The spectra had been signed up at λ = 260 nm in quartz cuvettes.… Continue reading Pharmacological agents suggested for infarct size limitation have severe unwanted effects
Tag: MDV3100
History miRNAs regulate gene expression at the post-transcriptional level. examining LC3II
History miRNAs regulate gene expression at the post-transcriptional level. examining LC3II formation using Western blot and confocal imaging. Results Both miR-106a and miR-106b mimics inhibited starvation-induced autophagy. miR-106b mimic reduced ATG16L1 protein expression. Luciferase reporter assays showed that mutating the binding sequence at the position 1036-1042 abrogated miR-106b regulation of ATG16L1 3’UTR luciferase activity. In… Continue reading History miRNAs regulate gene expression at the post-transcriptional level. examining LC3II