Mutations in ABCC6 (ATP-binding cassette subfamily C member 6) an orphan transporter expressed within the liver organ are the reason behind pseudoxanthoma elasticum. recessive disorder seen as a calcification of elastin fibers in connective tissue like the heart vasculature eye and skin [3]. Furthermore to vascular calcification [4] the mice with mutations also display various… Continue reading Mutations in ABCC6 (ATP-binding cassette subfamily C member 6) an orphan