Fludarabine (Flu) clofarabine (Clo) and busulfan (Bu) are found in allogeneic hematopoietic stem cell transplant (allo-HSCT). response and cell routine checkpoint activation through the ATM-CHK2-P53 (or P73) pathway or ATM-CHK2-cdc25-cdc2 FRAX597 pathway (2) histone adjustments and (3) triggered apoptosis pathway. The [Flu + Clo + Bu + SAHA] FRAX597 mixture causes mitochondrial external membrane permeabilization… Continue reading Fludarabine (Flu) clofarabine (Clo) and busulfan (Bu) are found in allogeneic