Mammalian sterile20-like kinases (MST1/2) are involved in stress-induced apoptosis signalling. inhibited MST2 relationships with Raf-1 but improved binding to RASSF1A leading to higher activation of downstream tension signalling pathways (JNK FK866 and p38 MAPK) and apoptosis. Biochemical and DNMT1 FLIM tests exposed a dual system of inhibition. Akt phosphorylation of MST2 (i) blocks binding to… Continue reading Mammalian sterile20-like kinases (MST1/2) are involved in stress-induced apoptosis signalling. inhibited