Objective The effect of antacid therapy for patients with COPD and gastroesophageal reflux disease (GERD) remains unclear. and 56,809.78 person-years, respectively, from 2000 to 2011. After multivariate adjustment, symptomatic GERD was associated with acute exacerbation (adjusted hazard ratio [HR]: 1.35, 95% CI: 1.23C1.48, test for non-normal distributions. bIncidence rate per 100 person-year. cExacerbation was measured… Continue reading Objective The effect of antacid therapy for patients with COPD and