The endoplasmic reticulum (ER) protein GT1 (UDP-glucose: glycoprotein glucosyltransferase) may be the central enzyme that modifies N-linked carbohydrates based on the properties from the polypeptide backbone from the maturing substrate. influenza hemagglutinin (HA) in the undamaged mammalian ER. GT1 reglucosylated N-linked glycans in the slow-folding stem site of HA after the nascent string was released… Continue reading The endoplasmic reticulum (ER) protein GT1 (UDP-glucose: glycoprotein glucosyltransferase) may be