Secreted factors and cell surface receptors can be internalized by endocytosis

Secreted factors and cell surface receptors can be internalized by endocytosis and translocated to the cytoplasm. their receptors are often detected in the nucleus of cancer cells. Nuclear localization of these molecules has been correlated with tumor progression and poor prognosis for patient survival. Nuclear growth receptors and factors could be in charge of resistance… Continue reading Secreted factors and cell surface receptors can be internalized by endocytosis

Having less success in target-based screening methods to the discovery of

Having less success in target-based screening methods to the discovery of antibacterial agents has resulted in reemergence of phenotypic screening as an effective approach of identifying bioactive, antibacterial compounds. distributed between the community, this validation of the focus on predictions gives excess weight to computational methods to set up the system of actions (MoA) of… Continue reading Having less success in target-based screening methods to the discovery of