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Neuronal nicotinic receptors, encoded by 9 genes from the alpha and

Neuronal nicotinic receptors, encoded by 9 genes from the alpha and 3 from the beta kind of subunits, and whose gene products assemble in specific permutations as pentameric molecules, constitute a fertile area for structure-guided drug design. not really preferentially bind. Ligand association at these user interface sites may modulate receptor function. Ligand binding can…