Chemically diverse fragments have a tendency to collectively bind at localized sites about proteins, which really is a cornerstone of fragment-based techniques. TAT-TAR protein-RNA relationships, as well as the MDM2-MDM4 differential binding to p53. The experimental confirmations of extremely nonobvious predictions combined with exact characterization of a wide selection of known phenomena give strong support… Continue reading Chemically diverse fragments have a tendency to collectively bind at localized